For performance and interoperability reason with existing packages it would be very welcome if react-native would support WASM or Webassembly. There have been efforts trying to get WASM to run with modules but as https://github.com/ExodusMovement/react-native-wasm illustrates, it is tough to get there.
(A good read is also https://github.com/polkadot-js/wasm/issues/19 - the struggle is real!)